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Research Programmes

 

Submicron Systems and Nanodevices

Doc. Ing. Jaromír Hubálek, Ph.D.
Research Group Leader

THEMATIC RESEARCH FOCUS

RESEARCH AREAS

  • Microdevices for sensoric applications
  • Nanomedicine
  • Lab on a chip
  • Bio-probes based on QDs, MNPs
  • Biosensors of nucleic acids, proteins, peptides

MAIN OBJECTIVES

Research and development of submicron devices and nanodevices

Development of methods and techniques for implementation of outputs into higher functional integrated systems, special electronic circuits on a chip, nano- and micro-electromechanical systems (MEMS/NEMS), bioprobes and (bio)sensors and advanced materials for them. Development of libraries for the design of integrated systems and their fabrication using CEITEC planar technologies, specifying new techniques and methods of packaging and testing of nanostructures and devices. Nanostructures implemented into these systems will enhance the performance and efficiency of current devices and systems and widen the areas of their applications (e.g. biosensors, biochips, biorecognition tranducers).

CONTENT OF RESEARCH

Research and development of submicron devices and nanodevices

Development of more complex systems, both electrical and electromechanical (MEMS/NEMS) with applications in sensing, diagnostics, etc.

Nanodevices and their integration into electronic systems

The implementation of the nanoelements and techniques into higher functional electronic units, design and integration of advanced RF communication systems on a chip for data transfer in in-vivo applications. Material and process optimisation, modelling and simulation of microelectronic units. The development of advanced microelectronic technologies for SMART microsystems and systems based on new materials for high frequency transmission. Designing models and technological libraries of the new structures, elements and devices. Investigation of the compatibility of the new techniques with current technologies and their optimisation for smooth incorporation into the technological procedures of the semiconductor industry.

Materials and advanced structures for MEMS/NEMS and sensors

Investigation of nanostructured materials and their characterisation with respect to their applications in sensors, designing MEMS and NEMS as the building blocks, transducers for chemical and biochemical recognition, and procedures of creating system units as compatible processes, as usually developed in the semiconductor industry. Techniques for assembling heterostructures to achieve compatible integration into submicron systems. Nanostructured arrays for biomolecular application with bioactive surfaces. MEMS systems for advanced fluidic systems integrated together with electronic detectors (lab-on-chip construction). Systems will be also developed for in-vivo and in-vitro analysis of biologically interesting substances. The work will also include protective layers on chips for medical application to achieve biocompatibility and to prevent negative interaction of the system (chip) with living substances/tissues of the organisms.

KEY RESEARCH EQUIPMENT

PLANNED RESEARCH INFRASTRUCTURE

Core Facilities

The research group will be one of the principal users of the equipment available within CEITEC Nanolithography and Nanofabrication and Nanocharacterisation Core Facilities.

Technology Units

Molecular chemistry and bioelectrochemistry

CURRENT RESEARCH INFRASTRUCTURE

Physical vapour deposition facility; SEM; experimental setups for electrochemical deposition and electrochemical analysis; instruments for testing the electrical properties of electronic devices and circuits; thick fi lm technology (screen-printing, ovens); mounting technology (soldering, packaging, ultrasound bonding, etc.); software Cadence – design and simulation of electronic chips.

MAIN PROJECTS

  • Miniaturized intelligent systems and nanostructured electrodes for chemical, biological, and pharmaceutical applications (NANIMEL) (GA102/08/1546), Czech Science Foundation, 2008-2012, J. Hubalek, Brno University of Technology, R. Kizek, Mendel University in Brno.
  • Impedimetric chemical microsensors with nanomachined surface of electrodes (1QS201710508), Academy of Sciences of the Czech Republic, 2005-2009, J. Hubalek, Brno University of Technology.
  • New design and exploiting nanobiosensors and nanosensors to target medicine (NANOSEMED) (KAN208130801), Academy of Sciences of the Czech Republic, 2008-2012, J. Hubalek, Brno University of Technology, A. Horna, RADANAL, Ltd., R. Kizek, Mendel University in Brno.

SELECTED PUBLICATIONS

  • FUJCIK, L., PROKOP, R., PRASEK, J., HUBALEK, J., VRBA, R. New CMOS potentiostat as ASIC for several electrochemical microsensors construction. Microelectronics International. 2010, 27(1), p. 3-10.
  • STEJSKAL, K., KRIZKOVA, S., ADAM, V., SURES, B., TRNKOVA, L., ZEHNALEK, J., HUBALEK, J., BEKLOVA, M., HANUSTIAK, P., SVOBODOVA, Z., HORNA, A., KIZEK, R. Bio-Assessing of Environmental Pollution via Monitoring of Metallothionein Level Using Electrochemical Detection. IEEE Sensors Journal. 2008, 8(9-10), p. 1578-1585.
  • KLOSOVA, K., HUBALEK, J. Advanced electrodes with nanostructured surfaces for electrochemical microsensors. Physica Status Solidi (a). 2008, 205(6), p. 1435-1438.
  • ZITKA, O., HUSKA, D., KRIZKOVA, S., ADAM, V., GRACE, C., TRNKOVA, L., HORNA, A., HUBALEK, J., KIZEK, R. An Investigation of Glutathione-Platinum(II) Interactions by Means of the Flow Injection Analysis Using Glassy Carbon Electrode. Sensors. 2007, 7(7), p. 1256-1270.
  • PRASEK, J., ADAMEK, M., HUBALEK, J., ADAM, V., TRNKOVA, L., KIZEK, R. New Hydrodynamic Electrochemical Arrangement for Cadmium Ions Detection Using Thick-Film Chemical Sensor Electrodes. Sensors. 2006, 6(11), p. 1498-1512.
 

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