Research Programmes
Do you know…
- … the scientists in CEITEC will be researching what happens in the brain when a human has realized that they have made a mistake?
- … there will be nearly 800 scientists in CEITEC?
- … in CEITEC we will be researching how the brain works and why some people are motivated and others are not?
- … thanks to CEITEC most of the diagnostic methods will be cheaper, faster and more comfortable for the patients?
- … 63 research teams will be created in CEITEC?
- … there will be 7 research programmes in CEITEC?
- … there will be more than 1,000 modern instruments in CEITEC?
- … more than 31,000 m2 of new infrastructure will be built in CEITEC?
- … more than 1,500 students will use the CEITEC infrastructure per year?
- … there will be 10 shared laboratories created in CEITEC?
- … CEITEC has 6 partners?
- … work will be carried out on self-cleaning surfaces in CEITEC?
- … CEITEC will co-operate closely with the industrial sector?
- … there will also be international scientists working in CEITEC?
- … CEITEC will support the international mobility of scientists?
- … the scientists in CEITEC are developing a subdermal chip which will analyse some life functions and will inform doctors from a distance?
- … the scientists in CEITEC are working on the development of a device which will enable physiotherapy from a distance?
- … the scientists at CEITEC are working on the development of biosensors?
- … CEITEC will be created in the south-Moravian city of Brno?
Psychophysiology
Prof. MUDr. Miloslav Kukleta, CSc.
Research Group Leader
THEMATIC RESEARCH FOCUS
RESEARCH AREAS
Main research interest of the Psychophysiology research group is the study of internal organisation of cognitive and motivational functions of the human brain
MAIN OBJECTIVES
- Analysis of temporospatial relations between components of brain potentials recorded during selected cognitive tasks.
- Analysis of EEG synchronisation between remote brain areas during defined functional states of the CNS.
- Nonlinear analysis of electroencephalographic and electrodermal data in the norm and pathology (chronic stress, states of drug abuse, psychiatric diseases).
- Study of possible participation of epileptiform activity in the development and maintenance of smoking habit.
CONTENT OF RESEARCH
Principles in neural connectivity underlying normal and pathological brain processing
Mechanisms of CNS adaptation on pathological factors and therapy
The participation of the research group within the work packages will consist mainly in the study of functional relationships in cognitive and motivational networks and of their changes induced by definite functional conditions of the brain. Using analysis of temporospatial relationships between components of EEG responses, analysis of synchronisation phenomena between remote brain areas and of other indicators obtained by nonlinear elaboration of EEG and electrodermal data and correlation of obtained results with relevant psychometric indicators will enable us to contribute to the understanding of internal organisation of higher brain functions. In the research of behavioral factors the endeavour of the research group is directed to deeper understanding of motivation mechanisms, which take place in the pathogeny of diseases associated with health habits such as diet, exercise, alcohol, and tabacco use and with health impact of chronic stress. Application of this approach to the study of selected pathological conditions should lead, considering possible suggestions, to the improvement of therapeutic interventions.
KEY RESEARCH EQUIPMENT
PLANNED RESEARCH INFRASTRUCTURE
Core Facility
The research group will be one of the principal users of the equipment available within CEITEC Molecular and Functional Imaging Core Facility.
CURRENT RESEARCH INFRASTRUCTURE
MR Siemens Magnetom Symphony 1.5T, MR compatible EEG (BrainAmp) 32 channels, Video EEG system (Alien) 128 channels, EEG system (BrainScope) 96 channels, EEG system BrainScope (32 channels) and, EEG and EDA system Psychlab.
MAIN PROJECTS
The Internal Organisation and Neurobiological Mechanisms of Functional CNS Systems under Normal and Pathological Conditions (MSM0021622404), Ministry of Education, Youth and Sports, 2005-2011, I. Rektor, Masaryk University.
SELECTED PUBLICATIONS
- SVETLAK, M., BOB, P., CERNIK, M., KUKLETA, M. Electrodermal complexity during the stroop colour word test. Autonomic Neuroscience: Basic and Clinical. 2010, 152, p. 101-107.
- KUKLETA, M., BOB, P., BRAZDIL, M., ROMAN, R., REKTOR, I. The level of frontal-temporal beta-2 band EEG synchronization distinguishes anterior cingulate cortex from other frontal regions. Consciousness and Cognition. 2010, 19, p. 879-886.
- BOB, P., SUSTA, M., GLASLOVA, K., BOUTROS, N., N. Dissociative symptoms and interregional EEG cross-correlations in paranoid schizophrenia. Psychiatry Research. 2010, 177, p. 37-40.
- BOB, P., SUSTA, M., GREGUSOVA, A., JASOVA, D. Dissociation, cognitive conflict and nonlinear patterns of heart rate dynamics in patients with unipolar depression. Progress in Neuro-Psychopharmacology a Biological Psychiatry. 2009, 33, p. 141-145.
- BOB, P. Pain, dissociation and subliminal self-representations. Consciousness and Cognition. 2008, 17, p. 355-369.
EUROPEAN UNION
