Bioinformatician / Computational biologist

Research Position | Published on 14.02.2024 | CEITEC MU

The Central European Institute of Technology (CEITEC), Masaryk University, CZ,

is announcing the opening of a postdoctoral position for a

Bioinformatician / Computational biologist

 

We are seeking a highly skilled bioinformatician / computational biologist with substantial expertise in plant genomics to contribute to a research project focusing on the in-depth analysis of genome structure and evolution in the genus Boechera (Brassicaceae). This role is essential for the three-year research project led by Dr. Terezie Mandakova and funded by the Czech Science Foundation.

Research project description:

The genus Boechera (Brassicaceae) comprises around 480 genetically distinct taxa, mainly distributed in North America. The genus includes diploid sexual species, as well as allodiploid and allotriploid apomicts. Heterochromatic apomixis-associated chromosomes have been identified in apomictic Boechera plants. Due to its small genome, close evolutionary relationship to Arabidopsis, and naturally occurring diploid sexual and diploid apomictic lines, the genus Boechera represents a unique model system for studying the genomic changes associated with apomixis. Recent improvements in long-read sequencing and algorithmic advances in genome assembly enable telomere-to-telomere genome assembly, including complex (peri)centromeric regions. Our goal is to analyse Boechera genomes using long-read sequencing methods to investigate links between hybridisation, chromosome reorganisation, and the evolution of apomixis. This project will provide in-depth evidence on the genome structure and evolutionary dynamism of apomictic Boechera genomes and will contribute to uncovering the genomic impact of apomixis. This will enable the development of more refined hypotheses about the underlying molecular mechanisms leading to the expression of apomixis in general.

The ideal candidate should possess the following qualifications:

  • PhD in a relevant scientific discipline such as genetics, genomics, molecular biology, mathematical biology or bioinformatics
  • Proficiency in genome sequencing methods
  • Hands-on experience analysing ONT, PacBio HiFi, and Hi-C data to conduct chromosome-level assemblies and genetic and epigenetic annotation
  • Excellent understanding of the plant genome structure and mechanisms of genome evolution
  • Strong publication record
  • Extensive experience in running individual research projects
  • Proficient in both spoken and written English
  • Experience in mentoring students
  • Exceptional communication skills, attention to detail, ability to work independently and collaboratively, self-motivation, adaptability, and a positive attitude

We provide:

  • An exceptional research topic in plant genomics
  • A collaborative environment that encourages interdisciplinarity and intersectoral research
  • A three-year postdoctoral position with a full-time (40 working hours/week) contract with the potential for further extension
  • Involvement in a project led by a highly motivated and enthusiastic principal investigator
  • An attractive salary
  • Flexible working hours
  • Remote work
  • No restriction on gender, nationality, age,  or current location
  • Welcome Office service before arrival
  • Grant Office service and support
  • Postdoc Committee Association  
  • Psychological counselling
  • CEITEC events – workshops, conferences, lectures, training, open day, family gathering
  • Medical insurance. 
  • Six weeks of paid holiday. 
  • Kindergarten in the next building. 
  • Contribution to a kindergarten or pension scheme. 
  • Meal contributions. 
  • A multisport card and sports lessons directly at the campus. 
  • Reduced prices for mobile operator tariffs. 
  • Special employee bank products. 

Anticipated start date: June 1st, 2024, or as mutually discussed.

Electronic application:

Interested candidates are invited to submit their applications here, comprising a CV, contact information for referees, and a motivation letter.

Application deadline: April 30th, 2024

HR contact: Lenka Divinová, e-mail: lenka.divinova@ceitec.muni.cz

We encourage you to apply if you are passionate about bioinformatics and plant genomics and eager to contribute to cutting-edge research in a collaborative environment. Your expertise will be crucial in advancing our understanding of genome structure and evolution within the genus Boechera (Brassicaceae). Be part of a vibrant scientific community and contribute to groundbreaking discoveries. Apply today and embark on a rewarding journey with us. We look forward to welcoming you to CEITEC!

Start date: May 1st, 2024 or as mutually discussed
Opened Until: 30.4.2024

I am interested