CEITEC TALK: Hierarchical Assembly of Biomimetic Synthetic Materials for Validated Organs on Chip
In biology and medicine, many advances have been made, and yet, many open questions remain. New technologies are needed to elucidate the mechanism governing development, to develop novel therapeutics, and to understand the mechanism of action of new drugs, among other applications. Organ-on-chip devices are one such technology that has the potential to revolutionize the fields of biology and medicine, and yet they are far from perfect. The development of novel biomaterials is needed to support further advancements of this technology and its application, particularly when trying to mimic more complex tissues. The talk will discuss creation of several types of materials, with different properties, for use in organ-on-chip devices with novel bone marrow-on chip and tooth-on-chip devices as tangible examples.