PhD Positions – Molecular Medicine Area

Research Position | Published on 04.12.2019 | CEITEC MU

The main goals of Molecular Medicine Area are to address the actual topics in current biomedical research and clinical medicine. They are focused on introduction of modern approaches of the genome analysis (human, as well as microbial), characterisation of cell behaviour on a molecular level, with emphasis on malignant transformation, and resistance to modern anti-cancer treatment, and analysis of mechanisms leading to disturbances of immune response.

Open PhD Positions:                                                                         

Topic Supervisor
1. ADAR2 RNA editing in CNS Liam Keegan
2. Characterization of cyclin-dependent kinase 12 (CDK12) substrates and their roles in regulation of transcription and tumorigenesis Dalibor Blažek

 3. Development of bioinformatics methods for data integration from various diagnostic types in clinical oncology

Vojtěch Bystrý
4. Elucidation of novel therapy targets for B-cell malignancies Michal Šmída
5. Functions of cyclin-dependent kinase 11 (CDK11) in regulation of gene expression Dalibor Blažek
6. Investigating the regulation of the RNA modifying enzyme ADAR1 and how it regulates other biological pathways and diseases Mary O’Connell
7. Long non-coding RNAs (lncRNAs) in the pathogenesis of B cell lymphomas Marek Mráz
8. Migration of malignant B cells and their adaptive response to BCR inhibitor therapy Marek Mráz
9. Non-coding RNAs (microRNAS/lncRNAS) and microenvironmental interactions of malignant B-cells Marek Mráz
10. Regulation of BCR signalling by DNA damage response and P53 protein Marek Mráz
11. The role of posttranscriptional RNA modifications in cell differentiation Štěpánka Vaňáčová
12. The role of protein-protein interactions in the dynamics of m6A RNA modification Štěpánka Vaňáčová


Successful candidate must hold the equivalent of a Master's degree (Mgr., Ing., MSc.) in the same or similar study programmes from an institution of recognized standing (four or five year undergraduate degree).

Detailed information available at:

Conditions and contact:

Starting date: September 2020

Complete applications can be submitted: until 20 February 2020

To apply please contact

Information about CEITEC PhD School

4-year program

Above-standard funding

State-of-the-art Core Facilities

International and interdisciplinary environment

Wide range of topics from experiences supervisors

Coursework in your chosen field, soft and transferable skills and bioinformatics

Information about Brno and Czech Republic

#4 most popular city in the world for students according to

#1 best city for expat support according to Financial Times

The capital of South Moravian Region and the second largest city in the Czech Republic with a population of almost 400,000 people

A city of universities with more than 86,000 students

City of Gregor Mendel, the founder of genetics

#6 safest country according to whitepaper on the future of Europe

EU, Schengen, NATO, OECD member

Information about Masaryk University

The second largest university in the Czech Republic, consisting of nine faculties

Extremely wide range of study possibilities

State-of-the-art equipment, cutting-edge technologies and international cooperation

A member of the Compostela Group and the Utrecht Network

Start date: September 2020
Opened Until: 20.2.2020

I am interested
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