PhD Positions - Structural Biology | CEITEC

Structural Biology area integrates information on the structure of biologically important macromolecules – proteins, nucleic acids and their complexes. Progressive high-resolution methods of structural analysis such as X-ray diffraction, nuclear magnetic resonance, cryo-electron microscopy and tomography are used in combination with modern methods of molecular modelling, theoretical chemistry, and bioinformatics.

Open PhD Positions:

Topic	Supervisor
A structural basis for the cross-talk between histones and RNA Polymerase II	Richard Štefl
Are Tau fibrils induced by phosphorylation and the interaction with 14-3-3 proteins relevant for Alzheimer disease?	Jozef Hritz
Cracking the CTD code	Richard Štefl
Designing modified DNA fragments	Radek Marek
Experimental and theoretical studies of the origin of life on the Earth	Jiří Šponer
Integrative structural biology of 3’UTRs	Peter Lukavsky
Interactions underlying physiological function of Microtubule Associated Protein 2c	Lukáš Žídek
Multiscale modelling of nucleic acids	Jiří Šponer
Protein motif for bacterial affinity	Robert Vácha
Protein sensitivity of membrane curvature	Robert Vácha
Regulation of protein-protein interactions	Robert Vácha
RNA as a drug target	Peter Lukavsky
Role of phosphorylated 14-3-3 proteins	Jozef Hritz
Structural and time-resolved studies of phage replication in bacterial biofilm	Pavel Plevka
Structural study of enterovirus replication in vivo	Pavel Plevka
Structural studies of the TPLATE complex	Konstantinos Tripsianes
Structure of parallel forms of nucleic acids studied by NMR spectroscopy and molecular modelling	Radek Marek
Structure, dynamics and interactions of bacterial RNA polymerase subunits and sigma factors	Lukáš Žídek
Structure-functional study of proteins involved in host cell recognition	Michaela Wimmerová
Tau conformational changes induced by phosphorylation and 14-3-3 proteins relevant in neurodegenerative diseases	Jozef Hritz

Requirements:

Successful candidate must hold the equivalent of a Master's degree (Mgr., Ing., MSc.) in the same or similar study programmes from an institution of recognized standing (four or five year undergraduate degree).

Detailed information available at: http://ls-phd.ceitec.cz/

Conditions and contact:

Starting date: September 2020

Complete applications can be submitted: until 20 February 2020

To apply please contact phd@ceitec.muni.cz

Information about CEITEC PhD School

4-year program
Above-standard funding
State-of-the-art Core Facilities
International and interdisciplinary environment
Wide range of topics from experiences supervisors
Coursework in your chosen field, soft and transferable skills and bioinformatics

Information about Brno and Czech Republic

#4 most popular city in the world for students according to topuniversities.com
#1 best city for expat support according to Financial Times
The capital of South Moravian Region and the second largest city in the Czech Republic with a population of almost 400,000 people
A city of universities with more than 86,000 students
City of Gregor Mendel, the founder of genetics
#6 safest country according to whitepaper on the future of Europe
EU, Schengen, NATO, OECD member

Information about Masaryk University

The second largest university in the Czech Republic, consisting of nine faculties
Extremely wide range of study possibilities
State-of-the-art equipment, cutting-edge technologies and international cooperation
A member of the Compostela Group and the Utrecht Network

PhD Positions - Structural Biology

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