PhD Positions - Structural Biology

Research Position | Published on 03.12.2019 | CEITEC MU

Structural Biology area integrates information on the structure of biologically important macromolecules – proteins, nucleic acids and their complexes. Progressive high-resolution methods of structural analysis such as X-ray diffraction, nuclear magnetic resonance, cryo-electron microscopy and tomography are used in combination with modern methods of molecular modelling, theoretical chemistry, and bioinformatics.

Open PhD Positions:



  1. A structural basis for the cross-talk between histones and RNA Polymerase II

Richard Štefl

  1. Are Tau fibrils induced by phosphorylation and the interaction with 14-3-3 proteins relevant for Alzheimer disease?

Jozef Hritz

  1. Cracking the CTD code

Richard Štefl

  1. Designing modified DNA fragments

Radek Marek

  1. Experimental and theoretical studies of the origin of life on the Earth

Jiří Šponer

  1. Integrative structural biology of 3’UTRs

Peter Lukavsky

  1. Interactions underlying physiological function of Microtubule Associated Protein 2c

Lukáš Žídek

  1. Multiscale modelling of nucleic acids

Jiří Šponer

  1. Protein motif for bacterial affinity

Robert Vácha

  1. Protein sensitivity of membrane curvature

Robert Vácha

  1. Regulation of protein-protein interactions

Robert Vácha

  1. RNA as a drug target

Peter Lukavsky

  1. Role of phosphorylated 14-3-3 proteins 

Jozef Hritz

  1. Structural and time-resolved studies of phage replication in bacterial biofilm

Pavel Plevka

  1. Structural study of enterovirus replication in vivo

Pavel Plevka

  1. Structural studies of the TPLATE complex

Konstantinos Tripsianes

  1. Structure of parallel forms of nucleic acids studied by NMR spectroscopy and molecular modelling

Radek Marek

  1. Structure, dynamics and interactions of bacterial RNA polymerase subunits and sigma factors

Lukáš Žídek

  1. Structure-functional study of proteins involved in host cell recognition

Michaela Wimmerová

  1. Tau conformational changes induced by phosphorylation and 14-3-3 proteins relevant in neurodegenerative diseases

Jozef Hritz





Successful candidate must hold the equivalent of a Master's degree (Mgr., Ing., MSc.) in the same or similar study programmes from an institution of recognized standing (four or five year undergraduate degree).

Detailed information available at:

Conditions and contact:

Starting date: September 2020

Complete applications can be submitted: until 20 February 2020

To apply please contact

Information about CEITEC PhD School

  • 4-year program
  • Above-standard funding
  • State-of-the-art Core Facilities
  • International and interdisciplinary environment
  • Wide range of topics from experiences supervisors
  • Coursework in your chosen field, soft and transferable skills and bioinformatics

Information about Brno and Czech Republic

  • #4 most popular city in the world for students according to
  • #1 best city for expat support according to Financial Times
  • The capital of South Moravian Region and the second largest city in the Czech Republic with a population of almost 400,000 people
  • A city of universities with more than 86,000 students
  • City of Gregor Mendel, the founder of genetics
  • #6 safest country according to whitepaper on the future of Europe
  • EU, Schengen, NATO, OECD member

Information about Masaryk University


Start date: September 2020
Opened Until: 29.2.2020

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