POSTDOC - Antimicrobial peptides

Research Position | Published on 24.09.2021 | CEITEC MU

Postdoctoral Fellow – Antimicrobial peptides

 

Central European Institute of Technology of Masaryk University (CEITEC MU) 

Brno, Czech Republic | www.ceitec.eu

 

We are the Czech Republic’s flagship basic research institute based at Masaryk University. Our modern in-house core facilities, which provide open access to the latest technologies and expertise, currently support more than 500 researchers from over 35 countries, who are together pushing the boundaries of knowledge in the areas of structural biology, molecular medicine, genomics and proteomics of plant systems, and neuroscience.

 

Our postdoctoral programme will enable you to participate in one of many exciting scientific projects addressing current global issues related to health and the quality of human life. You will have the opportunity to discuss and develop ideas and train your ability to reason in a scientific manner, formulate hypotheses independently, to innovate, and to perform independent research. It is an excellent opportunity to fully develop the skills acquired throughout your PhD studies. You will have access to a professional administration supporting you with grant preparation and administration, with technology transfer, science communication and with other areas of modern research management. You will have the chance to participate in a wide range of scientific and career development events and become a valued member of our vibrant multinational scientific community.

 

About this position 

Antimicrobial peptides (AMPs) can disrupt the membrane barrier function and kill bacteria, including resistant bacteria recognized by the UN and WHO as one of the biggest threats to global health. AMPs are part of the host-defense system of many organisms and promising candidates to become a new class of therapeutics. The aim of this project is to design new peptides that disrupt the membranes of pathogens. To obtain such peptides, we will establish the relationship between peptide sequence motifs and their ability to disrupt bacterial membranes. This ERC funded project will be complemented by experiments providing verification and feedback of membrane disruption. The main tool will be Molecular dynamics simulations with free energy calculations using Gromacs program package.

 

A postdoc position is available in the Robert Vácha lab (vacha.ceitec.cz; CEITEC, Masaryk University, Brno, Czech Republic). We are seeking a person with expertise in computer simulations of proteins or membranes and experience with all-atom or Martini models. Research will be conducted at CEITEC located in the life science campus of Masaryk University (Brno, Bohunice).

Requirements

  • PhD in computational biophysics/chemistry/physics and related fields
  • Theoretical knowledge of Molecular Dynamics
  • Some years of work experience in simulations with proteins/membranes and their analysis
  • Published in impactful journals in the field, corresponding to given stage of career demonstrating creativity and scientific quality
  • Good English language – spoken and written
  • Motivated person with collaborative mind set

We offer

  • An attractive salary condition
  • Medical insurance
  • 6 weeks of paid holiday
  • Contribution to a pension scheme
  • Flat-rate meal contributions
  • A multisport card and sports lessons directly at the campus
  • Reduced prices for mobile operator tariffs
  • Special employee bank products

 

We value our employees, and we support them from their very first day at CEITEC. We are an inclusive, equal opportunity employer and offer a highly collaborative, collegial and family friendly, international working environment with relocation assistance through our Welcome Office. The selected candidate will become a valued member of the CEITEC scientific community with access to in-house core facilities and professional administrative support. Have a look at what your potential peers say about working at CEITEC MU.

 

Brno is a lively city surrounded by beautiful countryside. It is a top destination for many educated expatriates working in the areas of science and technology. Brno is located in the heart of Europe and offers a great standard of living.

 

CEITEC MU is a proud holder of the European Commission’s HR Excellence in Research Award

What else you need to know

Application deadline: 30 June, 2022

Expected start date: negotiable

Hours: full time

Duration: fixed term

Eligibility criteria: only external candidates will be considered

 

Applications including a CV, list of publications, a scanned copy of the PhD diploma or an official letter certifying submission of a doctoral thesis defense and the planned defense date, brief motivation letter, and contacts for at least two references should be sent via e-application HERE.

 

In the case of any difficulties filling out the e-application, please contact Veronika Slezáková (veronika.slezakova@ceitec.muni.cz).

 

For more information about the recruitment process, refer to CEITEC MU Recruitment Policy.  

For more information about our career system, refer to CEITEC MU Career System.

 

In justified cases, the job announcer can extend, interrupt or cancel the selection procedure. 

Start date: negotiable
Opened Until: 30.6.2022

I am interested