Research Position | Published on 16.02.2021 |
The Director of Central European Institute of Technology (CEITEC MU) opens a position
POSTDOC - Scramble Selectivity
Description of project
Cell membranes are phospholipid bilayers with large amount of embedded transmembrane proteins. Some of these proteins, such as scramblases, have properties which facilitate lipid flip-flop from one membrane leaflet to another. We have shown that scramblases can facilitate not only spontaneous flip-flop of lipids but also a translocation of other amphiphilic molecules across cellular membranes. However, we miss information about the selectivity of this transport. The goal of this project is to determine selectivity and specificity of scramblase activity and obtain a molecular understanding of the selectivity. The main tool will be Molecular dynamics simulations with free energy calculations using Gromacs program package.
CEITEC is a scientific centre in the fields of life sciences, advanced materials and technologies whose aim is to establish itself as a recognized centre for basic as well as applied research. CEITEC offers a state-of-the-art infrastructure and great conditions to employ excellent researchers. Our institute values diversity and promotes an inclusive working environment with the aim to support the best scientists. CEITEC MU is a proud holder of the HR Excellence in Research Award by the European Commission. (http://muni.ceitec.cz/en/hr-strategy-hrs4r/)
A postdoc position is available in the Robert Vácha lab (vacha.ceitec.cz; CEITEC, Masaryk University, Brno, Czech Republic). We are seeking a person with expertise in computer simulations of proteins or membranes and experience with all-atom or Martini models. Research will be conducted at CEITEC located in the life science campus of Masaryk University (Brno, Bohunice, https://www.ceitec.eu/).
Anticipated start date: Negotiable
Application including CV, a brief motivation letter and contacts for referees should be sent by e-application available on https://www.muni.cz/en/about-us/careers/vacancies/60934.
In case of any questions about job offer, please contact: Robert Vácha (email@example.com).
In case of any troubles with filling the e-application, please contact: Veronika Slezáková (firstname.lastname@example.org).
Electronic application deadline is 31 March 2021.
Information about Brno, Czech Republic
For further information about:
Start date: negotiable
Opened Until: 31.3.2021