Přemysl Souček, Ph.D.

Přemysl Souček, Ph.D.

Senior Researcher

Contact

Email:
Phone: +420 54949 7567
Research group: Inherited Diseases - Transtricptional Regulation - Dalibor Blažek, Medical Genomics - Šárka Pospíšilová
Workplace:

2017

  • Analysis of changes in genome and its expression in chronic lymphocytic leukemia patients during the disease development (NS10439), Ministry of Health - Departmental Programme of Research and Development (2008-2011), 2009 - 2011
  • The role of the gene coding for TACI and abnormalities in lymphocyte subpopulations in the pathogenesis of IgA deficiency (NR10662), Ministry of Health - Branch programm of research of the Ministry of Health (2004-2009), 2009 - 2011
  • Screening of mutations and polymorphisms in neonatal Fc receptor gene in patients with primary disorders of antibody production (NR9192), Ministry of Health - Branch programm of research of the Ministry of Health (2004-2009), 2007 - 2009
  • Genetic determination of clinical manifestation in patients with hereditary angioedema (NR7921), Ministry of Health - Branch programm of research of the Ministry of Health (2004-2009), 2004 - 2006
  • Complement in the pathogenesis of autoimmune thyreopaties (NR10662), Ministry of Health - Branch programm of research of the Ministry of Health (2004-2009), 2009 - 2011
  • The roles of Cdk12 in ovarian tumorigenesis (MFR2013), Foundations - International - Marsha Rivkin Center, 2013 - 2014
  • Regulation and function of P-TEFb complexes (SRGA 454), South Moravian Region - SoMoPro, 2010 - 2013
  • Novel methylation of Hexim1 and cyclin composition of positive trancription elongation factor b (P-TEFb) regulate kinase activity of cdk9 (ME09047), MEYS - KONTAKT, 2009 - 2013
  • Nová izoforma cyklinu K je partnerem kinázy cdk12 regulující transkripci a alternativní sestřih u eukaryot (GAP305/11/1564), Grantová agentura ČR, 2011 - 2013
  • Funkční charakterizace unikátních zásobních ribonukleoproteinových částic v pylu (GAP501/11/1462), Grantová agentura ČR, 2011 - 2014
  • Real-time PCR soupravy pro diagnostiku v onkologii (FR-TI2/254), Ministerstvo průmyslu a obchodu ČR, 2010 - 2013
  • SuPReMMe - Podpora profesního růstu a mezinárodní integrace výzkumných týmů v oblasti molekulární medicíny (CZ.1.07/2.3.00/20.0045), Ministerstvo školství, mládeže a tělovýchovy ČR, 2011 - 2014
  • NGS-PTL - Next Generation Sequencing platform for targeted Personalized Therapy of Leukemia (306242), Evropská unie, 2012 - 2015
  • Involvement of nuclear HMGB proteins in sensitizing of human cells to anticancer drugs inhibiting DNA topoizomerases (GAP301/10/0590), Czech Science Foundation - Standard Grants, 2010 - 2012
  • Functional and structural changes of microRNAs in lymphoproliferative malignancies and their impact on prognosis and prediction of therapy response (NT11218), Ministry of Health - Ministry of Health´s Departmental Research and Development Programme III (2010-2015), 2010 - 2015
  • Functional and molecular characteristics of cancer and normal stem cells - identification of targets for novel therapeutics and therapeutic strategies (MSM0021622430), Ministerstvo školství, mládeže a tělovýchovy ČR, 2007 - 2013
  • Expression and function of activation-induced cytidine deaminase splice variants in normal B cell physiology and chronic lymphocytic leukemia (3SGA5792), Jihomoravský kraj, 2013 - 2016
  • Role Cdk12 a C-terminální domény RNA polymerázy II v transkripcně regulovaném procesu genomové nestability (GA14-09979S), Grantová agentura ČR, 2014 - 2016