Prof. Mary Anne O´Connell, Ph.D.

2019

• Wiatrek, DM; Candela, ME; Sedmik, JI; Oppelt, J; Keegan, LP; O´Connell, MA, 2019: Activation of innate immunity by mitochondrial dsRNA in mouse cells lacking p53 protein. RNA 25(6), p. 713 - 726, doi: 10.1261/rna.069625.118
• Sinigaglia, K; Wiatrek, D; Khan, A; Michalik, D; Sambrani, N; Sedmik, J; Vukic, D; O´Connell, MA; Keegan, LP, 2019: ADAR RNA editing in innate immune response phasing, in circadian clocks and in sleep. BIOCHIMICA ET BIOPHYSICA ACTA-GENE REGULATORY MECHANISMS 1862(3), p. 356 - 369, doi: 10.1016/j.bbagrm.2018.10.011

2018

• Jantsch, MF; Quattrone, A; O´Connell, M; Helm, M; Frye, M; Macias-Gonzales, M; Ohman, M; Ameres, S; Willems, L; Fuks, F; Oulas, A; Vanacova, S; Nielsen, H; Bousquet-Antonelli, C; Motorin, Y; Roignant, JY; Balatsos, N; Dinnyes, A; Baranov, P; Kelly, V; Lamm, A; Rechavi, G; Pelizzola, M; Liepins, J; Kholodnyuk, IH; Zammit, V; Ayers, D; Drablos, F; Dahl, JA; Bujnicki, J; Jeronimo, C; Almeida, R; Neagu, M; Costache, M; Bankovic, J; Banovic, B; Kyselovic, J; Valor, LM; Selbert, S; Pir, P; Demircan, T; Cowling, V; Schafer, M; Rossmanith, W; Lafontaine, D; David, A; Carre, C; Lyko, F; Schaffrath, R; Schwartz, S; Verdel, A; Klungland, A; Purta, E; Timotijevic, G; Cardona, F; Davalos, A; Ballana, E; O´Carroll, D; Ule, J; Fray, R, 2018: Positioning Europe for the EPITRANSCRIPTOMICS challenge. RNA BIOLOGY 15(6), p. 829 - 831, doi: 10.1080/15476286.2018.1460996
• O´Connell, M; Khan, A; Sambrani, N; Novakova, B; Keegan, L, 2018: Deciphering a novel role of ADAR in Drosophila development. FEBS OPEN BIO 8, p. 14 - 14

2017

• Keegan, L; Khan, A; Vukic, D; O´Connell, M, 2017: ADAR RNA editing below the backbone. RNA 23(9), p. 1317 - 1328, doi: 10.1261/rna.060921
• Bajad, P; Jantsch, MF; Keegan, L; O´Connell, M, 2017: A to I editing in disease is not fake news. RNA BIOLOGY 14(9), p. 1223 - 1231, doi: 10.1080/15476286.2017.1306173
• Quin, JE; Bujila, I; Cherif, M; Sanou, GS; Qu, Y; Homann, MV; Rolicka, A; Sirima, SB; O´Connell, MA; Lennartsson, A; Troye-Blomberg, M; Nebie, I; Farrant, AKO, 2017: Major transcriptional changes observed in the Fulani, an ethnic group less susceptible to malaria. ELIFE 6, doi: 10.7554/eLife.29156
• Gallo, A; Vukic, D; Michalik, D; O´Connell, MA; Keegan, LP, 2017: ADAR RNA editing in human disease; more to it than meets the I. HUMAN GENETICS 136(9), p. 1265 - 1278, doi: 10.1007/s00439-017-1837-0

2015

• Mannion, N; Arieti, F; Gallo, A; Keegan, LP; O´Connell, MA, 2015: New Insights into the Biological Role of Mammalian ADARs; the RNA Editing Proteins. BIOMOLECULES 5(4), p. 2338 - 2362, doi: 10.3390/biom5042338
• M. A. O’Connell; N. Mannion; L.P. Keegan, 2015: The Epitranscriptome and Innate Immunity. PLOS GENETICS 12(11), doi: 10.1371/journal.pgen.1005687

2014

• Mannion, NM; Greenwood, SM; Young, R; Cox, S; Brindle, J; Read, D; Nellaker, C; Vesely, C; Ponting, CP; McLaughlin, PJ; Jantsch, MF; Dorin, J; Adams, IR; Scadden, ADJ; Ohman, M; Keegan, LP; O´Connell, MA, 2014: The RNA-Editing Enzyme ADAR1 Controls Innate Immune Responses to RNA. CELL REPORTS 9(4), p. 1482 - 1494, doi: 10.1016/j.celrep.2014.10.041

2013

• Ramaswami, G; Zhang, R; Piskol, R; Keegan, LP; Deng, P; O´Connell, MA; Li, JB, 2013: Identifying RNA editing sites using RNA sequencing data alone. NATURE METHODS 10(2), p. 128 - 132, doi: 10.1038/NMETH.2330

2012

• Rice, GI; Kasher, PR; Forte, GMA; Mannion, NM; Greenwood, SM; Szynkiewicz, M; Dickerson, JE; Bhaskar, SS; Zampini, M; Briggs, TA; Jenkinson, EM; Bacino, CA; Battini, R; Bertini, E; Brogan, PA; Brueton, LA; Carpanelli, M; De Laet, C; de Lonlay, P; del Toro, 2012: Mutations in ADAR1 cause Aicardi-Goutieres syndrome associated with a type I interferon signature. NATURE GENETICS 44(11), p. 1243 - 1248, doi: 10.1038/ng.2414

2011

• Marcucci, R; Brindle, J; Paro, S; Casadio, A; Hempel, S; Morrice, N; Bisso, A; Keegan, LP; Del Sal, G; O´Connell, MA, 2011: Pin1 and WWP2 regulate GluR2 Q/R site RNA editing by ADAR2 with opposing effects. EMBO JOURNAL 30(20), p. 4211 - 4222, doi: 10.1038/emboj.2011.303

2010

• Galeano, F; Leroy, A; Rossetti, C; Gromova, I; Gautier, P; Keegan, LP; Massimi, L; Di Rocco, C; O´Connell, MA; Gallo, A, 2010: Human BLCAP transcript: new editing events in normal and cancerous tissues. INTERNATIONAL JOURNAL OF CANCER 127(1), p. 127 - 137, doi: 10.1002/ijc.25022

2009

• Heale, BSE; Keegan, LP; McGurk, L; Michlewski, G; Brindle, J; Stanton, CM; Caceres, JF; O´Connell, MA, 2009: Editing independent effects of ADARs on the miRNA/siRNA pathways. EMBO JOURNAL 28(20), p. 3145 - 3156, doi: 10.1038/sj.emboj.2009.244

• CEITEC - Central European Institute of Technology (CZ.1.05/1.1.00/02.0068), Ministerstvo školství, mládeže a tělovýchovy ČR, 2011 - 2015