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A small molecule drug promoting miRNA processing induces alternative splicing of MdmX transcript and rescues p53 activity in human cancer cells overexpressing MdmX protein  

PLOS ONE

Valianatos, G; Valcikova, B; Growkova, K; Verlande, A; Mlcochova, J; Radova, L; Stetkova, M; Vyhnakova, M; Slaby, O; Uldrijan, S, 2017: A small molecule drug promoting miRNA processing induces alternative splicing of MdmX transcript and rescues p53 activity in human cancer cells overexpressing MdmX protein. PLOS ONE 12(10), doi: 10.1371/journal.pone.0185801

Research Groups:

• Molecular Oncology - Solid Cancer

CEITEC authors:

• Lenka Radová, Ph.D.
• Prof. Ondřej Slabý, Ph.D.