The ERA Chair Culture as a Catalyst to Maximize the Potential of CEITEC
The lethal phenotype of Adar1 mutant mice and their rescue with Mavs.
Viability and liver integrity in Adar1 mutant fetal mice. (i-vi) Whole embryos of wildtype (i, iii, v) and Adar1 mutant (ii, iv, vi) progeny at E10.5 (i, ii), E11.5 (iii, iv) and E12.5 (v, vi). (vii-x) Whole embryo (vii, viii) and corresponding liver sections (ix, x) of wildtype (vii, ix) and Adar1 mutant (viii, x) progeny at E11.5. Fetal livers outlined by red boxes. Rescue of Adar1 mutant phenotypes inAdar1; Mavs double mutant mice. Gross visceral anatomy of Adar1−/−; Mavs−/− newborn mice. (xi) Appearance of pups at P0.5. (xii-xvi) Sections showing general visceral anatomy (xiv) with further detail of heart (xii), liver (xiii), intestines (xv) and rectum (xvi). Scale bars: i-viii, 1 mm; ix and x, 50 µm, xi,xiv, 3 mm; xii-xvi, 400 µm.
The ERA Chair project aims at supporting the on-going structural shift in the culture of the scientific community of Masaryk University by engaging a world-class scientific leader capable of inspiring positive change. Masaryk University has already been deeply involved in this process as the largest contributing member of the Central European Institute of Technology (CEITEC).
CEITEC is a scientific centre in the fields of the life sciences and advanced materials and technologies with the aim of establishing itself as a recognized centre for basic as well as applied research. The CEITEC consortium includes the most prominent universities and research institutes in Brno in the Czech Republic. Thanks to EU Structural Funds, CEITEC is currently in a very rapid stage of development. One of the challenges facing our organization will be to maximize the high potential that CEITEC has at its disposal through cross-disciplinary collaboration.
Within this proposal, we outline the intent to recruit an individual with the commitment to act as an agent of transformation to CEITEC and Masaryk University as a whole, and we will provide the eventual incumbent with a position and the means within the organisation to implement a robust cross-disciplinary program aimed at catalysing the creation of an open, dynamic scientific environment. Thus, we believe transformational leaders are an essential asset, not just for what they can achieve scientifically, but also how they can lead by example.
The project will be implemented through six work packages:
- Recruitment of an ERA Chair
- Operation of the ERA Chair research group
- Grants support system development
- Attractive scientific environment
- International outreach and dissemination
- Project management
Steering Comittee
