About event
Alex's lab studies how the human cell self-assembles the nucleus, the cells biggest organelle using novel integrated structural biology approaches. Within a few minutes following every cell division, countless molecules find their place in space and time to reassemble the membrane coated structure that is 10.000 times bigger in diameter than each of its parts. This process provides an example and great case study to dissect the unknown principles leading to the Structural Self-Organization of Membranous Organelles. Thus, the central question of his research is: “How do micron-spanning molecular patterns form and direct molecular activity with atomic precision?”. His major weapon of choice is Cryo-Electron Tomography, which he complements with state-of-the-art protein biochemistry, biophysical approaches and live imaging. This year, he was awarded the prestigious ERC Starting grant.
