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An ADAR1 dsRBD3-PKR kinase domain interaction on dsRNA inhibits PKR activation  

CELL REPORTS

Sinigaglia, K; Cherian, A; Du, QP; Lacovich, V; Vukic, D; Melicherová, J; Linhartova, P; Zerad, L; Stejskal, S; Malik, R; Prochazka, J; Bondurand, N; Sedlácek, R; O´Connell, MA; Keegan, LP, 2024: An ADAR1 dsRBD3-PKR kinase domain interaction on dsRNA inhibits PKR activation. CELL REPORTS 43(8), doi: 10.1016/j.celrep.2024.114618

Research Groups:

• ERA Chair - RNA and Immunity

CEITEC authors:

• Ketty Sinigaglia
• Anna Cherian
• Qiupei Du
• Valentina Lacovich Strašil, Ph.D.
• Dragana Vukić, Ph.D.
• Janka Melicherová
• Prof. Mary Anne O´Connell, Ph.D.
• Liam Keegan, Ph.D.