Lecture Seminar Series

BioIT Seminar: Computational Analyses and Functional Annotations of Non-Model Bacteria for White Biotechnology

About event

White biotechnology, i.e., a technology that uses living cells to synthesize easily degradable products, is the key to the transition from a linear oil-based to a circular bio-based economy. Suitable microbes are selected by their potential functional capacity revealed by computational analyses of their genomes. Nevertheless, bioinformatics analyses of non-model organisms are specific because many computational tools require the use of datasets that are unavailable for novel bacteria due to non-existing microbiological kits to perform desired experiments or simply due to missing knowledge of required input data. As there are hundreds of computational tools and packages to perform various kinds of bioinformatics analyses providing different results, their combination is usually needed to infer novel knowledge. In this talk, we’ll go through some basic steps in analyses of bacterial genomes, we’ll show how to combine multiple tools, and we’ll try to adjust current methods to datasets they were not originally designed for.

Date

15. 3. 2023, 16:00 - 17:00
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Online stream

Speaker

Karel Sedlář
Institut für Informatik, Ludwig-Maximilians-University of Munich, Germany

Venue

FI MUNI, Botanická 68a, Room A319