Daniel Zicha received his MSc from the Czech University of Technology, Prague with thesis on “Expert system for genetic diagnosis”. He then pursued a PhD project on “Artificial intelligence methods in tumour cell biology” at the Institute of Molecular Genetics, Czech Academy of Sciences. His subsequent postdoctoral research post, focussing on chemotaxis [Zicha, D. et al. (1991) A new direct viewing chemotaxis chamber. J Cell Sci 99 769-75] and development of interference microscopy [Dunn, G. A., and Zicha, D. (1997) Using the DRIMAPS system of interference microscopy to study cell behavior. In Handbook of Cell Biology (2nd edition), J. E. Celis (ed.), Academic Press Inc.], was held at Medical Research Council, Muscle and Cell Motility Unit, King's College, London, UK. Daniel Zicha has been head of Light Microscopy at Imperial Cancer Research Fund/ Cancer Research UK London Research Institute/ the Francis Crick Institute, Lincoln's Inn Fields Laboratory for over 17 years and since 2016, senior researcher at Brno University of Technology, CEITEC - Central European Institute of Technology, Czech Republic. He has been involved in development of novel quantitative light microscopy techniques such as “Fluorescence Localisation After Photobleaching” [Zicha, D. et al. (2003) Rapid actin transport during cell protrusion. Science 300 142 5] and has experience with metastasis research [Cavanna, T., Pokorná, E., Veselý, P., Gray, C., and Zicha, D. (2007) Evidence for protein 4.1B acting as a metastasis suppressor. J Cell Sci 120 606-16]. Daniel Zicha has been a member of the editorial board of the Journal of Microscopy since 2007.