Lecture: NMR as a Discovery Tool in Cell Biology

22. 2. 16:00, 2018
room 132, building A11, University Campus Bohunice
Phil Selenko, Leibniz Institute of Molecular Pharmacology, Berlin, Germany

Life Sciences Seminar Series


We use NMR spectroscopy to directly study proteins in live cells. Having established the experimental reference frame for investigating the human amyloid protein alpha-synuclein in healthy neuronal and non-neuronal cells, I present new data on the fate and basic biological function(s) of this protein in different mammalian cell types. Our results reveal surprising new insights into the role of alpha-synuclein in binding to unique physiological membranes.