Štěpánka Vaňáčová, Ph.D.

2018

• Jantsch, MF; Quattrone, A; O´Connell, M; Helm, M; Frye, M; Macias-Gonzales, M; Ohman, M; Ameres, S; Willems, L; Fuks, F; Oulas, A; Vanacova, S; Nielsen, H; Bousquet-Antonelli, C; Motorin, Y; Roignant, JY; Balatsos, N; Dinnyes, A; Baranov, P; Kelly, V; Lamm, A; Rechavi, G; Pelizzola, M; Liepins, J; Kholodnyuk, IH; Zammit, V; Ayers, D; Drablos, F; Dahl, JA; Bujnicki, J; Jeronimo, C; Almeida, R; Neagu, M; Costache, M; Bankovic, J; Banovic, B; Kyselovic, J; Valor, LM; Selbert, S; Pir, P; Demircan, T; Cowling, V; Schafer, M; Rossmanith, W; Lafontaine, D; David, A; Carre, C; Lyko, F; Schaffrath, R; Schwartz, S; Verdel, A; Klungland, A; Purta, E; Timotijevic, G; Cardona, F; Davalos, A; Ballana, E; O´Carroll, D; Ule, J; Fray, R, 2018: Positioning Europe for the EPITRANSCRIPTOMICS challenge. RNA BIOLOGY 15(6), p. 829 - 831, doi: 10.1080/15476286.2018.1460996
• Covelo-Molares, H; Bartosovic, M; Vanacova, S, 2018: RNA methylation in nuclear pre-mRNA processing. WILEY INTERDISCIPLINARY REVIEWS-RNA 9(6), doi: 10.1002/wrna.1489
• Zigackova, D; Vanacova, S, 2018: The role of 3 ´ end uridylation in RNA metabolism and cellular physiology. PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES 373(1762), doi: 10.1098/rstb.2018.0171
• Rajecka, V; Skalicky, V; Vanacova, S, 2018: The role of RNA adenosine demethylases in the control of gene expression. BIOCHIMICA ET BIOPHYSICA ACTA (BBA) - GENE REGULATORY MECHANISMS

2017

• Bartosovic, M; Molares, HC; Gregorova, P; Hrossova, D; Kudla, G; Vanacova, S, 2017: N6-methyladenosine demethylase FTO targets pre-mRNAs and regulates alternative splicing and 3´-end processing. NUCLEIC ACIDS RESEARCH 45(19), p. 11356 - 11370, doi: 10.1093/nar/gkx778

2016

• Ustianenko, D; Pasulka, J; Feketova, Z; Bednarik, L; Zigackova, D; Fortova, A; Zavolan, M; Vanacova, S, 2016: TUT-DIS3L2 is a mammalian surveillance pathway for aberrant structured non-coding RNAs. EMBO JOURNAL 35(20), p. 2179 - 2191, doi: 10.15252/embj.201694857

2015

• Hrossova, D; Sikorsky, T; Potesil, D; Bartosovic, M; Pasulka, J; Zdrahal, Z; Stefl, R; Vanacova, S, 2015: RBM7 subunit of the NEXT complex binds U-rich sequences and targets 3 ´-end extended forms of snRNAs. NUCLEIC ACIDS RESEARCH 43(8), p. 4236 - 4248, doi: 10.1093/nar/gkv240

2014

• Tudek, A; Porrua, O; Kabzinski, T; Lidschreiber, M; Kubicek, K; Fortova, A; Lacroute, F; Vanacova, S; Cramer, P; Stefl, R; Libri, D, 2014: Molecular Basis for Coordinating Transcription Termination with Noncoding RNA Degradation. MOLECULAR CELL 55(3), p. 467 - 481, doi: 10.1016/j.molcel.2014.05.031

2013

• Ustianenko, D; Hrossova, D; Potesil, D; Chalupnikova, K; Hrazdilova, K; Pachernik, J; Cetkovska, K; Uldrijan, S; Zdrahal, Z; Vanacova, S, 2013: Mammalian DIS3L2 exoribonuclease targets the uridylated precursors of let-7 miRNAs. RNA-A PUBLICATION OF THE RNA SOCIETY 19(12), p. 1632 - 1638, doi: 10.1261/rna.040055.113

2012

• Holub P., Vanacova S., 2012: TRAMP stimulation of exosome. In The Enzymes: Eukaryotic RNases and their Partners in RNA Degradation and Biogenesis, Part A. ELSEVIER INC. (31), p. 77 - 95
• Kubicek, K; Cerna, H; Holub, P; Pasulka, J; Hrossova, D; Loehr, F; Hofr, C; Vanacova, S; Stefl, R, 2012: Serine phosphorylation and proline isomerization in RNAP II CTD control recruitment of Nrd1. GENES & DEVELOPMENT 26(17), p. 1891 - 1896, doi: 10.1101/gad.192781.112
• Holub, P; Lalakova, J; Cerna, H; Pasulka, J; Sarazova, M; Hrazdilova, K; Arce, MS; Hobor, F; Stefl, R; Vanacova, S, 2012: Air2p is critical for the assembly and RNA-binding of the TRAMP complex and the KOW domain of Mtr4p is crucial for exosome activation. NUCLEIC ACIDS RESEARCH 40(12), p. 5679 - 5693, doi: 10.1093/nar/gks223

2011

• Sanudo, M; Jacko, M; Rammelt, C; Vanacova, S; Stefl, R, 2011: H-1, C-13, and N-15 chemical shift assignments of ZCCHC9. BIOMOLECULAR NMR ASSIGNMENTS 5(1), p. 19 - 21, doi: 10.1007/s12104-010-9257-2
• Hobor, F; Pergoli, R; Kubicek, K; Hrossova, D; Bacikova, V; Zimmermann, M; Pasulka, J; Hofr, C; Vanacova, S; Stefl, R, 2011: Recognition of Transcription Termination Signal by the Nuclear Polyadenylated RNA-binding (NAB) 3 Protein. JOURNAL OF BIOLOGICAL CHEMISTRY 286(5), p. 3645 - 3657, doi: 10.1074/jbc.M110.158774

2009

• PAOLO, S., S., VANACOVA, S., SCHENK, L., SCHERRER, T., BLANK, D., KELLER, W., GERBER, A., P., 2009: Distinct roles of non-canonical poly(A) polymerases in RNA metabolism. PLOS GENETICS 5(7)

• Integrativní studium molekulárních mechanismů epitranskriptomu savčích buněk, Ministerstvo školství, mládeže a tělovýchovy ČR, 2018 - 2021
• Úloha komplexu TRAMP4 při tvorbě 3´ konců mRNA v kvasince Saccharomyces cerevisiae (GA17-20388S), Grantová agentura ČR, 2017 - 2019
• Studium úlohy uridylace v lidských buňkách, Czech Science Foundation - Standard Grants, 2016-2018 (16-21341S), , 2019 - 2019
• Cerpani grantu Wellcome Trust bylo oficialne prodlouzeno do roku 2017, , 2019 - 2019
• Characterization of the RNA substrate repertoir of the human demethylase FTO, Czech Science Foundation - Standard Grants, 2014-2016 engl. (14-25884S), , 2019 - 2019
• Studium úlohy uridylace RNA v lidských buňkách (GA16-21341S), Grantová agentura ČR, 2016 - 2018
• Polyadenylation and mechanisms of nuclear RNA quality control (084316/Z/07/Z), Wellcome Trust, 2008 - 2018
• Proměna endosymbionta na organelu (GA13-29423S), Grantová agentura ČR, 2013 - 2016
• Charakterizace substrátového repertoáru RNA lidské demetylázy FTO, Grantová agentura ČR, 2014 - 2016
• CEITEC - Central European Institute of Technology (CZ.1.05/1.1.00/02.0068), Ministerstvo školství, mládeže a tělovýchovy ČR, 2011 - 2015
• Zaměstnáním čerstvých absolventů doktorského studia k vědecké excelenci (CZ.1.07/2.3.00/30.0009), Ministerstvo školství, mládeže a tělovýchovy ČR, 2012 - 2015
• Strukturní podstata ukončení transkripce nezávislé na poly(A) signálu (GAP305/10/1490), Grantová agentura ČR, 2010 - 2014
• Functional and biochemical characterization of Dis3L2, the third mammalian homolog of the key yeast exosome nuclease Dis3p (GAP305/11/1095), Grantová agentura ČR, 2011 - 2014
• EMBO Young Investigator Programme (1642), EMBO (European Molecular Biology Organization), 2008 - 2010