Escape of Tick-Borne Flavivirus from 2´-C-Methylated Nucleoside Antivirals Is Mediated by a Single Conservative Mutation in NS5 That Has a Dramatic Effect on Viral Fitness

JOURNAL OF VIROLOGY

Eyer, L; Kondo, H; Zouharova, D; Hirano, M; Valdes, JJ; Muto, M; Kastl, T; Kobayashi, S; Haviernik, J; Igarashi, M; Kariwa, H; Vaculovicova, M; Cerny, J; Kizek, R; Kroger, A; Lienenklaus, S; Dejmek, M; Nencka, R; Palus, M; Salat, J; De Clercq, E; Yoshii, K; Ruzek, D, 2017: Escape of Tick-Borne Flavivirus from 2´-C-Methylated Nucleoside Antivirals Is Mediated by a Single Conservative Mutation in NS5 That Has a Dramatic Effect on Viral Fitness. JOURNAL OF VIROLOGY 91(21), doi: 10.1128/JVI.01028-17

Research Groups:

• Smart Nanodevices - Jaromír Hubálek

CEITEC authors:

• Markéta Vaculovičová, Ph.D.