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Kafka wrote of alienation leaving us emotionally estranged as we see what happens to people once their identity is broken. Could this happen to proteins as well if the scientific community disregards their true nature and isolates them from what they are supposed to be? Alpha-synuclein, a protein highly connected to Parkinson’s disease, is called intrinsically disordered, however, one simple acetylation and a Nobel Prize-winning experiment often forgotten, show us there is much more to identity of this protein than just a simple statement of it being disordered.
