About event
A two-day conference is organized in memory of our esteemed colleague and one of the most prominent and internationally recognized experts in the field of NMR and structural biology, Professor Vladimír Sklenář, who passed away on 13 April 2024. At the Central European Institute of Technology (CEITEC), Masaryk University, he was instrumental in establishing world-class research infrastructures in structural biology, particularly in NMR spectroscopy and electron microscopy. CIISB has established itself at the level of comparable workplaces in Western Europe thanks to his interactions with the Instruct-ERIC, European ESFRI infrastructure, where he acted as a member of the Executive Committee and Council. His tenure at the Faculty of Science of Masaryk University, CIISB and CEITEC was characterized by a great passion for scientific challenges and a great deal of humanity with which he approached his colleagues.
Lectures and contributions by invited speakers will bring back memories of Vladimir’s tenure and will present the latest scientific findings in structural biology and in NMR.
Speakers
Andrew Atkinson, IPBS-Toulouse;
Lucia Banci, CERM Florence;
Adriaan Bax, National Institutes of Health;
Martin Blackledge, IBS CNRS, France;
Rolf Boelens, Utrecht University;
Juli Feigon, University of California;
Christian Griesinger, MPI Goettingen;
Michal Hocek, IOCB Prague;
Wiktor Koźmiński, University of Warsaw;
Norbert Müller, Johannes Kepler University Linz;
Jiří Nováček, CEITEC MUNI & Chair of CIISB;
Hartmut Oschkinat, FMP Berlin;
András Perczel, Eötvös Loránd University;
Vladimír Saudek, Cambridge University;
Lukáš Trantírek, CEITEC MUNI;
Václav Veverka, IOCB Prague;
Lukáš Žídek, NCBR SCI & CEITEC MUNI
Programme
November 14, 2024
12:00–13:00 | Registration |
13:00–13:45 |
Ceremonial Section Šárka Pospíšilová, Vice-rector for research and doctoral studies, Masaryk University Pavel Plevka, Director of CEITEC MUNI Ctirad Hofr, Vice-Dean for Research and Internationalization, Faculty of Science Jan Dohnálek, Deputy Chair of CIISB Radovan Fiala, CEITEC MUNI: Vladimír Sklenář Memorial Stipend |
13:45–14:00 | Coffee break |
14:00–16:30 |
Lecture Session 1 |
14:00–14:45 | Adriaan Bax: Protein NMR: past, present, and future |
14:45–15:30 | Juli Feigon: When Vladi met Juli |
15:30–16:30 | Vladimír Saudek and Andrew Atkinson: Vladimír Sklenář in Strasbourg: Origins of Watergate and Other Adventures (1992-1995) |
16:30–17:00 | Coffee break |
17:00–18:40 | Lecture Session 2 |
17:00–17:25 | András Perczel: NMR-driven studies and drug development to target KRAS |
17:25–17:50 | Christian Griesinger: Structural insight into protein aggregation in lipids and its modulation by small molecules |
17:50–18:15 | Hartmut Oschkinat: Extending the range of NMR in the spirit of Vladi |
18:15–18:40 | Martin Blackledge: NMR provides unique insight into the functional dynamics of intrinsically disordered proteins |
18:40 | Buffet dinner |
November 15, 2024
9:00–10:00 | Lecture Session 3 |
9:00–9:20 | Václav Veverka: Essential interactions of intrinsically disordered regions in histone chaperones during transcription elongation |
9:20–9:40 | Michal Hocek: Base-modified nucleic acids for chemical biology |
9:40–10:00 | Norbert Müller: The activation mechanism of the human STIM1 calcium channel protein studied by solution NMR |
10:00–10:15 | Coffee break |
10:15–11:15 | Lecture Session 4 |
10:15–10:35 | Lucia Banci: in-cell NMR within Integrated Structural Biology |
10:35–10:55 | Rolf Boelens: A tale of Lac and NMR |
10:55–11:15 | Wiktor Koźmiński: Non-uniform sampling and IDPs |
11:15–11:30 | Coffee break |
11:30–12:30 | Lecture Session 5 |
11:30–11:50 | Jiří Nováček: CIISB: Structural Biology in service mode |
11:50–12:10 | Lukáš Žídek: What can we learn about disordered proteins? Microtubule Associated Protein 2c as an example |
12:10–12:30 | Lukáš Trantírek: Towards Physiological State-Resolved NMR Spectroscopy |
12:30–13:30 | Lunch to go |