The structure of a protein is closely linked to its function, but a static image alone is often not enough to understand how a protein actually works. Proteins are dynamic molecules that change shape and interact with each other. Some also contain intrinsically disordered regions that do not adopt a single stable three-dimensional structure. This ability to change their spatial arrangement can be essential for a protein to function properly. We therefore study not only protein structure, but also protein dynamics and interactions with other molecules.
Antibiotics are used therapeutically to fight bacterial infections. Most antibiotics are of natural origin or their…
Supervisor
Tau is an intrinsically disordered microtubule-associated protein that maintains neuronal structure and stability.…
Supervisor
Prof. Lukáš Žídek, Ph.D.
Jozef Hritz, Ph.D.
