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The Biophotonics Core Facility was established in 2023 and delivers state-of-the-art services offering Holographic Incoherent-light-source Quantitative Phase Imaging (hiQPI) and Laser Scanning Confocal Microscopy and cell culture in the immediate vicinity of the microscopes. The focus is on leveraging cutting-edge technology, including the latest hiQPI Q-Phase from Telight and 2024 obtained user-friendly and high-performance laser scanning confocal microscope LSM 980 from Zeiss. The facility has extensive experience with supporting the techniques since the hiiQPI was designed in-house and members of staff were using the Zeiss LSM previously.
The main focus of the facility is studying and analyzing the responses of live cells in cell culture. Proficiency is demonstrated in providing hiQPI, a label-free technique, ideally suited for live tissue culture cells, with unparalleled precision of quantitation. The integration of LSM introduces distinctive capabilities for correlated imaging alongside hiQPI. As follows we offer data management encompassing long-term storage, advanced image processing, and comprehensive data analysis.
Our specialized and dedicated light microscopy service, with support for sample preparation and bespoke data processing, is constantly being enhanced to address the diverse needs of future research challenges of facility users.
The Biophotonics Core Facility is a part of the biological imaging section of the Czech-Bioimaging (national research infrastructure, which also covers medical imaging, consisting of distributed leading imaging facilities in the Czech Republic). Our facility is also a part of the Brno node within Euro-Bioimaging.
Czech-BioImaging is a national research infrastructure for biological and medical imaging. It is a distributed infrastructure of leading imaging facilities in the Czech Republic. The infrastructure provides an open access to a wide range of imaging technologies and expertise to all scientists in the Czech Republic and from abroad by a unified and coordinated logistics approach.
Users from the Czech Republic and abroad may apply access into laboratory and its services via Czech-BioImaging open access - see the Czech-BioImaging web site and Euro-BioImaging open access - see the Euro-BioImaging web site.
