Molecular Medicine

The main goal of the Molecular Medicine Area is to gain better understanding of basic molecular mechanisms in many diseases, especially cancer. Researchers of the programme focus on various types of leukaemia and several solid tumours, they investigate immune cell microenvironment, transcription regulation, B and T cell receptor repertoires, and the effect of RNA modifications on innate immunity. For various malignancies, much effort has also been made to identify diagnostic and prognostic markers (miRNA profiling, lincRNA, mutations in TP53and other cancer-related genes) and introduce them in clinical practice.