Phage replication in bacterial biofilm

  • Acronym: BioPhage
  • Project Type: ERC CZ
  • Project Coordinator: CEITEC MU
  • Grant Provider/Investor: The Ministry of Education, Youth and Sports
  • Project Code: LL1906
  • Implementation Period: 01. 01. 2020 – 31. 12. 2024
  • Budget: 2 292 702,25 EUR

Project Description: 

The ability of bacteria to form biofilms complicates their treatment. Bacteriophages can infect and kill bacteria in biofilm, but the use of phages as medicines prevents a lack of knowledge of their biology. We will determine the mechanisms underlying the phage propagation in biofilm and the assembly of phage progeny in the infected cells. We describe the course of phage infection in clinically relevant conditions and allow the development of new drugs.

Principal Investigator:

Pavel Plevka, Ph.D. Pavel Plevka, Ph.D. Research Group Leader Senior
Phone: +420 54949 7756
Email:
Office:



Read More

25. Nov. 2019

Bacteriophages Could Help Against Antibiotic Resistance

Dominik Hrebik, in collaboration with his colleagues from CEITEC Masaryk University, described the structure of the phage P68, known for its ability…

5. Oct. 2016

SCIENTIST FROM CEITEC WERE THE FIRST TO DESCRIBE HOW A BACTERIOPHAGE PENETRATES STAPHYLOCOCCUS AUREUS CELLS

The biologist Pavel Plevka not only deals with the studies of viruses but he also researches the ways how viruses penetrate cells and how new…

2. Dec. 2019

Jak zničit zlatého stafylokoka, který odolá i antibiotikům? Nemocným dává naději fág P68

Vědecký tým pod vedením Dominika Hrebíka z brněnského institutu CEITEC dokázal popsat vlastnosti bakteriofágu, který si dokáže bez problémů…