Tomáš Loja, Ph.D.

Tomáš Loja, Ph.D.

Senior Staff Scientist


iNEXT-Discovery: Infrastructure for transnational access and discovery in integrated structural biology (871037), , 2020 - 2024
Signaling propensity in the microenvironment of B cell chronic lymphocytic leukemia , Evropská unie, 2019 - 2024
Creating synergies between research infrastructures to stimulate innovation in the cross-border region (ATCZ40), Ministerstvo pro místní rozvoj ČR, 2016 - 2020
Národní centrum lékařské genomiky (LM2015091), Ministerstvo školství, mládeže a tělovýchovy ČR, 2016 - 2019
Profiling DNA structure and DNA ligand interactions inside nuclei of live mammalian cells by in-cell NMR spectroscopy. , Masarykova univerzita, 2018 - 2019
NCLG - Národní centrum lékařské genomiky - modernizace infrastruktury a výzkum genetické variability populace (CZ.02.1.01/0.0/0.0/16_013/0001634), Ministerstvo školství, mládeže a tělovýchovy ČR, 2017 - 2019
Cellular Structural Biology of non-B DNA Motifs in Human Genome (2535), EMBO (European Molecular Biology Organization), 2013 - 2017
Cílená terapie proti rezistentím kmenovým buňkám gliomového nádoru - kontrola přísunu živin pomocí iontových kanálů (GA15-20818S), Grantová agentura ČR, 2015 - 2017
Towards selective targeting of DNA G-quadruplexes by small molecular weight ligands within the human genome (4SGA8580), Jihomoravský kraj, 2014 - 2017
Evolucne konzervované strukturní vlastnosti centromerické a telomerické DNA (GA13-28310S), Grantová agentura ČR, 2013 - 2016
Expression and function of activation-induced cytidine deaminase splice variants in normal B cell physiology and chronic lymphocytic leukemia (3SGA5792), Jihomoravský kraj, 2013 - 2016
Environmentally COntrolled POlymorphism of non-B DNA structures (322104), Evropská unie, 2012 - 2016
Analysis of EGFR signalling and microRNA expression profiles in prediction of response to anti-EGFR (NT/13860), Ministry of Health - Ministry of Health´s Departmental Research and Development Programme III (2010-2015), 2012 - 2015
MicroRNA analysis in glioblastoma stem cells: prediction of therapy response and identification of new therapeutic targets in glioblastoma patients (NT/13514), Ministry of Health - Ministry of Health´s Departmental Research and Development Programme III (2010-2015), 2012 - 2015
Complex characterization of molecular genetic changes in glioblastoma multiforme and its relapses, and evaluation of their possible significance in oncologic therapy and therapy effect (NT/13581), Ministry of Health - Ministry of Health´s Departmental Research and Development Programme III (2010-2015), 2012 - 2015
Functional and structural changes of microRNAs in lymphoproliferative malignancies and their impact on prognosis and prediction of therapy response (NT11218), Ministry of Health - Ministry of Health´s Departmental Research and Development Programme III (2010-2015), 2010 - 2015
Studium mikroRNA a genů asociovaných s procesem epiteliálně-mezenchymální tranzice jako potenciálních markerů pro predikci rizika a časný záchyt metastazování u pacientů s renálním karcinomem (NT13547-4/2012), Ministry of Health of the CR, 2012 - 2015
Development of diagnostic panel of circulating microRNAs for non-invasive early diagnostics and follow-up of colorectal cancer patients (NT/13549), Ministry of Health - Ministry of Health´s Departmental Research and Development Programme III (2010-2015), 2012 - 2015
NGS-PTL - Next Generation Sequencing platform for targeted Personalized Therapy of Leukemia (306242), Evropská unie, 2012 - 2015
Development of microRNA diagnostic panel for identification Barret esophagus patients at high-risk of progression to adenocarcinoma (NT13585), Ministry of Health - Ministry of Health´s Departmental Research and Development Programme III (2010-2015), 2012 - 2014
SuPReMMe - Podpora profesního růstu a mezinárodní integrace výzkumných týmů v oblasti molekulární medicíny (CZ.1.07/2.3.00/20.0045), Ministerstvo školství, mládeže a tělovýchovy ČR, 2011 - 2014
Real-time PCR soupravy pro diagnostiku v onkologii (FR-TI2/254), Ministerstvo průmyslu a obchodu ČR, 2010 - 2013
Functional and molecular characteristics of cancer and normal stem cells - identification of targets for novel therapeutics and therapeutic strategies (MSM0021622430), Ministerstvo školství, mládeže a tělovýchovy ČR, 2007 - 2013
Identification and functional characterization of microRNAs with predictive significance in patients with glioblastoma (NT/11214), Ministry of Health - Ministry of Health´s Departmental Research and Development Programme III (2010-2015), 2010 - 2013
Involvement of nuclear HMGB proteins in sensitizing of human cells to anticancer drugs inhibiting DNA topoizomerases (GAP301/10/0590), Czech Science Foundation - Standard Grants, 2010 - 2012
Analysis of changes in genome and its expression in chronic lymphocytic leukemia patients during the disease development (NS10439), Ministry of Health - Departmental Programme of Research and Development (2008-2011), 2009 - 2011

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