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A class III ligand oscillates between internal and terminal binding modes as it engages with the Dishevelled PDZ domain

STRUCTURE

Kumar, J; Micka, M; Komarek, J; Klumpler, T; Bystry, V; Sprangers, R; Barinka, C; Bryja, V; Tripsianes, K, 2025: . STRUCTURE 33(8), doi: 10.1016/j.str.2025.05.012

Research Groups:

• Bioinformatics Core Facility
• Biomolecular Interactions and Crystallography Core Facility
• Protein-DNA Interactions
• Proteomics Core Facility
• Josef Dadok National NMR Centre
• Genomics Core Facility
• Biological Data Management and Analysis Core Facility

CEITEC authors:

• Jitender Kumar, Ph.D.
• Miroslav Micka
• Tomáš Klumpler, Ph.D.
• Vojtěch Bystrý, Ph.D.
• Konstantinos Tripsianes, Ph.D.