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Assembly and maturation of flaviviruses
| Supervisor | Pavel Plevka, Ph.D. |
| Research Group | Structural Virology |
The project will investigate how flavivirus particles assemble and mature into infectious virions. Using cryo-electron microscopy, cryo-electron tomography, and complementary biochemical approaches, the work will characterize structural intermediates of virus assembly and maturation and determine how viral proteins, membranes, and host-cell factors regulate these processes.
See list of topics
- Assembly and maturation of flaviviruses
- Cell entry and genome delivery of non-enveloped viruses
- Design principles of fusogenic proteins for lipid vesicles
- Development of advanced MRI techniques for functional brain mapping
- Frascan II: methods and applications
- How whole-genome triplication shaped desert adaptation in Brassiceae
- Integrating osteological and biomolecular evidence to investigate chromosomal aneuploidies in past populations
- Lipid nanoparticles in drug delivery
- Method development in palaeoproteomics
- Next-generation anticancer therapies based on metallodrugs
- One protein to rule them all: Decoding the multifunctionality of paramyxovirus matrix proteins
- Pushing the frontiers of magnetic resonance spectroscopy for biotechnology and materials engineering
- Regulation of drought stress memory and resilience in Brassica napus plants
- Retrogene evolution in Brassicaceae: The roles of genomic context and polyploid history
- RNA-associated mechanisms in Polycomb-mediated epigenetic silencing
- Tracing brain disease back to developmental decisions
- Translation Control