Cell entry and genome delivery of non-enveloped viruses

Supervisor Pavel Plevka, Ph.D.
Research Group Structural Virology

The postdoc will investigate how parvoviruses or polyomaviruses enter host cells and deliver their genomes. Using advanced cryo-electron microscopy and tomography, combined with fluorescence microscopy and molecular biology methods, the work will identify viral structural transitions and cellular factors that determine whether viral entry leads to productive infection or an abortive pathway.

See list of topics
  1. Assembly and maturation of flaviviruses
  2. Cell entry and genome delivery of non-enveloped viruses
  3. Design principles of fusogenic proteins for lipid vesicles
  4. Development of advanced MRI techniques for functional brain mapping
  5. Frascan II: methods and applications
  6. How whole-genome triplication shaped desert adaptation in Brassiceae
  7. Integrating osteological and biomolecular evidence to investigate chromosomal aneuploidies in past populations
  8. Lipid nanoparticles in drug delivery
  9. Method development in palaeoproteomics
  10. Next-generation anticancer therapies based on metallodrugs
  11. One protein to rule them all: Decoding the multifunctionality of paramyxovirus matrix proteins
  12. Pushing the frontiers of magnetic resonance spectroscopy for biotechnology and materials engineering
  13. Regulation of drought stress memory and resilience in Brassica napus plants
  14. Retrogene evolution in Brassicaceae: The roles of genomic context and polyploid history
  15. RNA-associated mechanisms in Polycomb-mediated epigenetic silencing
  16. Tracing brain disease back to developmental decisions
  17. Translation Control