Sdílet
The future of deep brain stimulation in the treatment of parkinson's disease
| Supervisor | Martin Lamoš, Ph.D. |  |
| Research Group | Multi-modal and Functional Neuroimaging |
This fellowship is based at the Multimodal and Functional Neuroimaging at Masaryk University (Martin Lamoš, Ivan Rektor) Our research focuses on developing novel noninvasive electrical stimulation methods for the central nervous systems, using advanced high-frequency (kHz) supraphysiological waveforms aimed at improving treatments for Parkinson’s disease and related movement disorders. We combine clinical studies in patients and healthy volunteers with theory and computational modelling. Our teams have access to advanced electrophysiology, medical imaging, and unique opportunities to work with patients carrying deep brain stimulation (DBS) implants, enabling both acute and chronic recordings from implanted electrodes. Collaboration with the Bioelectronics Materials and Devices group (Prof. E. Glowacki) at the Brno University of Technology CEITEC campus is also envisioned as a part of this project. A successful fellowship can be tailored to individual expertise, ranging from theoretical and computational modelling, through fundamental biophysics of kHz stimulation, to preclinical electrophysiology and clinical studies with human participants.
See list of topics
- Advanced software for batch processing of correlative imaging with quantitative phase and fluorescence
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- Advancing time-resolved cryo-EM to elucidate insulin receptor inhibition mechanisms
- Atomically engineered materials for sustainable carbon-free fuels
- Development and application of novel technology and/or characterization methods
- Development of multimaterial 3D printing using the digital light processing method
- Environmental “double trouble”: Elucidating plant molecular responses to heavy metal and PFAS co-contamination
- Exploring high-frequency electrical neurostimulation beyond classical mechanisms
- Exploitation of novel functional properties of surfaces/nanostructures in nanophotonics, nanoelectronics and/or quantum technologies
- FAST-4D hiQPI: Fast, accurate, scalable time-lapse 4D holographic incoherent-light-source quantitative phase imaging
- Genetic predispositions to development of hematological malignancies
- Characterization of electrochemical double layers...
- In situ magneto-ionic control of antiferromagnetic/ferromagnetic interfaces
- Investigation of novel possibilities for targeted therapy in acute myeloid leukemia
- Long non-coding RNAs in microenvironmental interactions of B cell chronic lymphocytic leukemia
- Magnetic actuation platforms for biological environments
- Magneto-structural properties and quantum phenomena in molecular materials
- Manipulation and detection of molecular magnets at 2D van der Waals interface
- Molecular mechanisms of heat stress adaptation...
- Nanorobots for biomedical and environmental applications
- Next generation materials for flexible wearable sensors and energy storage
- Next-generation noninvasive neurostimulation technologies
- Postdoctoral researcher in structural virology
- Processing of carbide-based ceramics by upcycling ceramic waste
- Pushing thin-film deposition techniques beyond their conformality limits
- Radical-free photocrosslinkable hydrogels for 3D bioprinting
- Role of transcription factors in B-cell malignancies
- Structural changes in intrinsically disordered proteins
- The future of deep brain stimulation in Parkinson’s disease
- Transformers applications for industrial systems faults detection
- Translation control
- Tuning the bioactivity of carbon-based coatings and nanoparticles
- Unravelling microplastic fate and transport
- Upcycling of ceramic waste to produce carbide-based ceramics